Antibodies targeting transient receptor potential vanilloid 1 as potential drug candidates for the treatment of chronic pain

Chronic pain is a major global health problem. The drugs that are currently used to treat the condition have limitations, such as side effects and insufficient pain relief. Therefore, research is underway to develop therapeutic antibodies that can target pain receptors. One receptor that has been of great interest for its involvement in chronic pain is transient receptor potential vanilloid …

The Aluminium Complex’s Ability to Bind Phosphorus in Acidic Conditions

Eutrophication poses threats to aquatic ecosystems, necessitating effective mitigation methods. This study has evaluated the efficacy of aluminium treatment in reducing eutrophication under acidic conditions in various water bodies using spectrophotometry and gravimetry. Results indicate a correlation between increased precipitation mass and reduced orthophosphate levels at higher pH. This correlation is due to pH-dependent equilibrium reactions. Acidification below pH 5.7 …

Is it appropriate to talk about ‘Reconquista’ in the History of Spain? Answer through dialogic analysis

The suitability of the term ‘Reconquista’ (Reconquest) represents an urgent problem in Spanish society due to its questioned political use, its potential ideological charge, its ambiguous official definition and its potential oversimplification. From the innovative methodology of dialogical analysis, four novel theses on the term ‘Reconquista’ are constructed to better understand this phenomenon: ‘Reconquista’ as an operational term, ‘Reconquista’ as …

Bioethics and Protection of Human Dignity in Research and Healthcare

The aim of this project is to study the degree of knowledge and awareness of the bioethical guidelines established at International, European and National level that seek to protect human dignity. Thus, in the first place, it carries out a historical review about some of the events that led to the creation of bioethical norms as well as a review …

No more Itaewon crowd crush disaster: Safety in dense crowds transformed by ‘KOSMOS’ service with AI reinforcement learning

“The 2022 Itaewon crushing incident raised public safety concerns. In response, we developed KOSMOS, an AI service addressing “”crowd turbulence””. It employs a reinforcement learning-based AI, designed to suggest routes for crowd dispersion and collision minimization. Our model’s effectiveness in suggesting safe, efficient routes was verified through a simulation that recreated the Itaewon incident using Seoul’s road data. The KOSMOS …

Effects of Compounds in Life on Antibiotic-Resistant Bacteria

Chemical stress on compounds was pointed out as one of the causes of bacterial antibiotic-resistance and observed in S. aureus whether various substances in daily life affect changes in the antibiotic-resistance. It has been confirmed that pesticides and heavy metal ions such as Cr ion affect antibiotic resistance. In addition, even though each of the two substances that does not …

The meaning of graphic symbols and brand affiliation

In our research project we created a new corporate graphic image of Secondary School of Mechanical Engineering, Mechatronics, and Media about what is important for successful brand marketing. With the help of surveys and interviews we researched the view of students of ŠCC SMM, teachers and other high school students on the appearance and graphic image of our school. It …

The impact of energy drinks on heart rate recovery

This study aimed to determine if there was a significant difference in heart rate recovery (HRR) after consuming an energy drink during sport activity. Male subjects aged 17-18 participated in standardized aerobic exercises, categorized as athletically active or inactive based on V02 max measured by Beep test. Each group consumed a caffeine, sugar and taurine-containing energy drink and a placebo …

Remediation of polychlorinated biphenyls (PCBs) and heavy metals via sustainable removal techniques

The escalating pollution by polychlorinated biphenyls (PCBs) and heavy metals highlights the urgency of finding sustainable remediation methods. Our research therefore aimed to investigate sorption and phytoremediation techniques. Our results indicate the necessity of a complex geochemical survey in contaminated areas. In the most affected sites, we suggest the use of activated charcoal, optimal for both PCBs (98.14%), and heavy …